Table 3.
Stability of different liposomal encapsulated rhodomyrtone formulations.
| Total lipid (µmol/mL) | Test (month) | Temp. (°C) | Particle size (nm) | ζ-potential (mV) | Entrapment efficacy (%) | Physical appearance |
|---|---|---|---|---|---|---|
| 60 | 0 | 25 | 209.56 ± 4.8 | −41.19 ± 1.3 | 65.47 ± 1.7 | Milky suspension |
| 2 | 4 | 217.72 ± 4.1 | −34.62 ± 1.3 | 64.57 ± 1.9 | Milky suspension | |
| 25 | 220.76 ± 4.9 | −35.98 ± 2.4 | 61.88 ± 1.1 | Yellow color of milky suspension | ||
| 4 | 4 | 261.24 ± 7.7 | −34.78 ± 1.5 | 64.94 ± 3.2 | Milky suspension | |
| 25 | 264.10 ± 6.7 | −34.36 ± 1.2 | 61.73 ± 2.8 | Yellow color of milky suspension | ||
| 6 | 4 | 262.60 ± 9.3 | −34.91 ± 2.2 | 65.49 ± 2.4 | Milky suspension | |
| 25 | 283.26 ± 8.3 | −35.96 ± 1.6 | 57.06 ± 3.1 | Slightly viscous of yellow milky suspension | ||
|
| ||||||
| 80 | 0 | 25 | 262.24 ± 5.6 | −46.29 ± 1.2 | 53.60 ± 1.2 | Milky suspension |
| 2 | 4 | 419.21 ± 1.7 | −32.36 ± 1.1 | 51.87 ± 1.4 | Milky suspension | |
| 25 | 421.63 ± 0.9 | −38.10 ± 1.6 | 46.66 ± 1.2 | Slightly viscous of yellow milky suspension | ||
|
| ||||||
| 100 | 0 | 25 | 274.64 ± 0.7 | −50.34 ± 1.3 | 63.05 ± 0.8 | Milky suspension |
| 2 | 4 | 438.71 ± 1.3 | −45.54 ± 1.5 | 60.91 ± 1.5 | Slightly viscous of yellow milky suspension | |
| 25 | 459.43 ± 1.4 | −41.96 ± 1.8 | 60.57 ± 0.9 | Slightly viscous of yellow milky suspension | ||
The results are the mean of three independent experiments ± S.E.