Table V.

Sensitivities and specificities of various blood fractions after maximal measurement errors were taken into account (CI, confidence interval)

Fraction	Value (µg/l)	Sensitivity (95% CI)	Specificity (95% CI)
Abnormal wear defined as ≥ 2 mm3/year (maximum over measurement)
Blood cobalt	4.50	0.904 (0.811 to 0.955)	0.944 (0.720 to 1.000)
Blood chromium	7.85	0.863 (0.763 to 0.925)	0.944 (0.720 to 1.000)
Serum cobalt	6.30	0.859 (0.751 to 0.926)	0.929 (0.661 to 1.000)
Serum chromium	7.30	0.891 (0.787 to 0.948)	0.929 (0.661 to 1.000)
Abnormal wear defined as ≥ 2 mm3/year (maximum under measurement)
Blood cobalt	4.50	0.929 (0.839 to 0.972)	0.905 (0.696 to 0.984)
Blood chromium	7.85	0.886 (0.787 to 0.943)	0.905 (0.696 to 0.984)
Serum cobalt	6.30	0.902 (0.797 to 0.957)	0.941 (0.707 to 1.000)
Serum chromium	7.30	0.902 (0.797 to 0.957)	0.824 (0.580 to 0.944)
Abnormal wear defined as ≥ 3 mm3/year (maximum over measurement)
Blood cobalt	5.04	0.928 (0.837 to 0.972)	0.955 (0.762 to 1.000)
Blood chromium	8.37	0.884 (0.784 to 0.942)	0.955 (0.762 to 1.000)
Serum cobalt	6.30	0.917 (0.814 to 0.967)	0.944 (0.720 to 1.000)
Serum chromium	7.70	0.917 (0.814 to 0.967)	0.889 (0.657 to 0.979)
Abnormal wear defined as ≥ 3 mm3/year (maximum under measurement)
Blood cobalt	5.04	0.941 (0.853 to 0.981)	0.957 (0.770 to 1.000)
Blood chromium	8.37	0.897 (0.799 to 0.951)	0.957 (0.770 to 1.000)
Serum cobalt	6.30	0.932 (0.832 to 0.977)	0.947 (0.732 to 1.000)
Serum chromium	7.70	0.932 (0.832 to 0.977)	0.895 (0.671 to 0.981)