Table 1.
Effect of nicotine on basal arterial BP and body weight.
| Animal group | BW(g) | n | SBP(mmHg) | n | DBP(mmHg) | n | MAP(mmHg) | n | HR(bpm) | n |
|---|---|---|---|---|---|---|---|---|---|---|
| Sham | ||||||||||
| Saline | 228.2±8.1 | 10 | 147.2±4.0 | 6 | 113.0±5.3 | 6 | 124.0±3.5 | 6 | 379.3±16.4 | 6 |
| Nicotine | 292.5±6.2 | 12 | 144.2±4.8 | 6 | 111.0±3.3 | 6 | 122.3±2.5 | 6 | 392.0±16.0 | 6 |
| OVX | ||||||||||
| Saline | 367.0±16.0 | 10 | 146.7±4.7 | 6 | 111.3±5.3 | 6 | 124.4±4.7 | 5 | 367.2±12.9 | 6 |
| Nicotine | 352.7±12.5 | 11 | 159.2±4.9 | 6 | 111.3±1.9 | 6 | 128.0±2.3 | 5 | 365.5±8.7 | 6 |
| OVX + E2 | ||||||||||
| Saline | 301.8±8.7 | 10 | 129.8±8.2 | 6 | 90.3±3.2 | 6 | 102.5±3.9 | 6 | 348.8±6.9 | 6 |
| Nicotine | 314.6±4.9 | 10 | 142.5±5.7 | 6 | 96.7±3.3 | 6 | 112.8±3.9 | 6 | 345.0±7.7 | 6 |
BW, body weight; SBP, systolic blood pressure; DBP, diastolic BP; MAP, mean arterial BP; HR, heart rate; n, animal numbers.