Skip to main content
. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: J Trauma Acute Care Surg. 2013 Jun;74(6):1454–1461. doi: 10.1097/TA.0b013e3182905ed2

Figure 1. Early systemic hyperinflammatory response to peripheral tissue trauma is TLR4-and TLR2-dependent, but TLR9-independent.

Figure 1

Plasma IL-6 (A) and plasma alanine aminotranferase (ALT) (B) in WT, TLR9-mutant, TLR4−/−, TLR2−/− mice at 6hr following pseudofracture (PF) or in unmanipulated controls. Data shown as mean±SEM; * = p < 0.05 vs. respective control; n=4–9 mice/group at each time point; representative of 2 independent experiments.