Table 2.
Studies reporting on the association between adult height and breast cancer risk stratified by race
| Reference | Age | Study Design | Sample Size | Exposure | Contrast | White | AA | Adjusted Covariates | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Risk Estimate | 95% CI | Risk Estimate | 95% CI | A | B | H | R | ||||||
| Palmer et al (1995)24 | 25–69 | PCC | AA: 681/1155 | Height (inches) | ≥71 vs 64 | N/A | 1.2 | 0.5–2.9 | X | P | |||
| <60 vs 64 | 0.3 | 0.2–0.7 | |||||||||||
| Premenopausal | ≥68 vs 64–65 | 0.7 | 0.4–1.2 | ||||||||||
| <61 vs 64–65 | 0.4 | 0.2–0.8 | |||||||||||
| Postmenopausal | ≥68 vs 64–65 | 1.1 | 0.6–2.3 | ||||||||||
| <61 vs 64–65 | 0.5 | 0.3–1.0 | |||||||||||
| Hall et al (2000)25 | 20–74 | PCC | AA: 350/353 W: 523/471 |
Height (cm) | 165.1–188 vs 140–160 | ||||||||
| Premenopausal | 0.77 | 0.46–1.29 | 2.93 | 1.44–5.95 | X | X | P | ||||||
| Continuous | 0.99 | 0.95–1.02 | 1.05 | 1.00–1.10 | |||||||||
| Postmenopausal | 1.63 | 0.96–2.76 | 1.00 | 0.55–1.83 | X | X | X | ||||||
| Continuous | 1.03 | 1.00–1.07 | 1.00 | 0.97–1.04 | |||||||||
| Palmer et al (2001)12 | 18–69 | PC (NCC) | 64,530 AA: 910/4535 |
Adult height (inches) | ≥ 70 vs ≤61 | 1.6 | 1.1–2.3 | X | P | ||||
| Premenopausal | 2.1 | 1.2–3.6 | |||||||||||
| Postmenopausal | 1.3 | 0.6–2.5 | |||||||||||
| Only incident cases | 3.0 | 1.3–6.5 | X | X | P | ||||||||
| John et al (2010)26 | ≥35 | PCC | AA:154/160 W: 143/165 |
Current height (cm) | Race-specific Q4 vs Q1 | 1.81 | 0.87–3.74 | 1.39 | 0.65–2.94 | X | P | ||
Abbreviations: PC: prospective cohort; PCC: population based case-control study; NCC: nested case-control study; W: White; AA: African American
Key Covariates: A: age; B: Body Mass Index; H: hormone use; R: reproductive factors (age at menarche, age at menopause, parity); X: adjusted for that covariate; P: partially adjusted for reproductive factors.