. Author manuscript; available in PMC: 2013 Jun 3.

Published in final edited form as: Public Health Nutr. 2011 Nov 29;15(4):738–748. doi: 10.1017/S136898001100303X

Table 3.

Studies reporting on the association between other anthropometric characteristics (current body mass index, body mass index at age 18, and waist-to-hip ratio) and breast cancer risk stratified by race

Reference	Age	Study Design	Sample Size	Exposure	Contrast	White		AA		Adjusted Covariates
						Risk Estimate	95% CI	Risk Estimate	95% CI	A	B	H	R
Current/Recent Body Mass Index
Schatzkin et al (1987)²⁷	25–70	PCC	AA:529/589	BMI	≥30 vs ≤24	N/A				X	X		P
					Premenopausal			1.2	0.7–2.1
					Postmenopausal			2.5	1.5–4.4
Mayberry (1994)²⁸	20–54	PCC	AA: 490/485	BMI as an adult	≥32.30 vs <24.90	N/A				X	X		P
					20–39 yrs of age			3.9	1.3–11.6
					40–54 yrs of age			0.8	0.4–1.4
Brinton et al (1997)¹⁶	20–54	PCC	AA: 281/296 W: 960/1033	Current BMI	<22.0 vs >28.8					X			P
					20–39 yrs of age	1.5	0.9–2.5	1.3	0.5–3.1
					40–54 yrs of age	1.2	0.9–1.8	0.8	0.3–1.9
Hall et al (2000)²⁵	20–74	PCC	AA: 350/353 W: 523/471	Current BMI	30.13–59.26 vs 14.62–24.61
					Premenopausal	0.46	0.20–0.80	0.89	0.38–2.07	X			P
					Postmenopausal	1.08	0.58–2.00	0.68	0.33–1.42	X			X
Zhu et al (2005)²⁹	20–64	PCC	AA:304/305	BMI at reference date	≥30 vs <25	N/A							P
					Premenopausal			2.49	0.87–7.59
					Postmenopausal			2.32	1.04–5.19
Palmer et al (2007)¹³	21–69	PC	59,000 AA: 1062 cases	Current BMI	≥35 vs <25	N/A				X	X		X
					Premenopausal			0.87	0.62–1.21
					Postmenopausal			0.99	0.72–1.36
John et al (2010)²⁶	≥35	PCC	AA:154/160 W: 143/165 (Only includes premenopausal women)	Quartile of current weight (kg)	>81.6 vs ≤61.2	0.55	0.23–1.34	1.62	0.26–1.14	X			P
			AA:154/160 W: 143/165 (Only includes premenopausal women)	Current BMI	≥30 vs <25	0.60	0.28–1.30	0.65	0.35–1.23
Berstad et al (2010)³⁰	35–64	PCC	AA:1622/1661 W:2953/3021	Recent BMI	35+ vs <25					X	X		P
					Premenopausal	0.86	0.57–1.29	0.81	0.56–1.19
					Postmenopausal	0.75	0.53–1.06	1.26	0.85–1.85
Body Mass Index at Age 18
Mayberry (1994)²⁸	20–54	PCC	AA: 490/485	BMI at age 18	≥30.70 vs <23.80	N/A				X	X		P
					20–39 yrs of age			0.5	0.2–1.4
					40–54 yrs of age			1.5	0.9–2.7
Zhu et al (2005)²⁹	20–64	PCC	AA:304/305	BMI at age 18	≥30 vs <25	N/A
					Premenopausal			1.84	0.27–12.45
					Postmenopausal			1.35	0.20–9.15
Palmer et al (2007)¹³	21–69	PC	59,000 AA: 1062 cases	BMI at age 18	≥25 vs <20	N/A				X	X		X
					Premenopausal			0.68	0.46–0.98
					Postmenopausal			0.53	0.35–0.81
Berstad et al (2010)³⁰	35–64	PCC	AA:1622/1661 W:2953/3021	BMI at age 18	25+ vs <20					X	X		P
					Premenopausal	0.84	0.61–1.15	0.67	0.47–0.96
					Postmenopausal	0.70	0.49–1.00	0.80	0.54–1.19
Waist-to-Hip-Ratio
Hall et al (2000)²⁵	20–74	PCC	AA: 350/353 W: 523/471	Waist/hip ratio	0.86–1.34 vs 0.60– 0.77
					Premenopausal	2.44	1.17–5.09	2.50	1.10–5.67	X	X		P
					Continuous	1.04	1.01–1.08	1.05	1.00–1.10
					Postmenopausal	1.64	0.88–3.07	1.62	0.70–3.79	X	X		X
					Continuous	1.03	1.00–1.06	1.03	0.99–1.07
Palmer et al (2007)¹³	21–69	PC	59,000 AA: 1062 cases	Waist circumference (in)	≥37 vs <28	N/A				X	X		X
					Premenopausal			1.04	0.73–1.48
					Postmenopausal			1.05	0.73–1.51
				Waist-to-hip ratio	≥0.87 vs <0.71					X	X		X
					Premenopausal			1.19	0.87–1.64
					Postmenopausal			0.99	0.72–1.37
John et al (2010)²⁶	≥35	PCC	AA:154/160 W: 143/165	Quartile of waist-to-hip ratio	>0.85 vs ≤0.77	1.35	0.47–3.86	0.82	0.39–1.74	X			P
			(only premenopausal)	Quartile of waist circumference (cm)	>98 vs ≤78.7	0.90	0.37–2.17	1.09	0.47–2.52	X			P

Abbreviations: PC: prospective cohort; PCC: population based case-control study; W: White; AA: African American

Key Covariates: A: age; B: Body Mass Index; H: hormone use; R: reproductive factors (age at menarche, age at menopause, parity); X: adjusted for that covariate; P: partially adjusted for reproductive factors.