Table 4.

Studies reporting on the association between physical activity and breast cancer risk stratified by race

Reference	Age	Study Design	Sample Size	Exposure	Contrast	White		AA		Adjusted Covariates
						Risk Estimate	95% CI	Risk Estimate	95% CI	A	B	H	R
Adams-Campbell et al (2001)31	21–69	PCC	AA: 704/1408	Strenuous exercise in high school (hrs/week)	7+ hrs/wk vs <1 hrs/wk	N/A				X	X		P
					Premenopausal			1.0	0.6–1.6
					Postmenopausal			1.1	0.6–2.1
				Strenuous exercise at age 21 (for diagnosis at age ≥30)	Premenopausal			0.5	0.3–0.8
					Postmenopausal			0.6	0.3–1.2
				Strenuous exercise at age 30 (for diagnosis at age ≥40)	Premenopausal			0.5	0.2–1.1
					Postmenopausal			0.5	0.2–1.2
				Strenuous exercise at age 40 (for diagnosis at age ≥50)	Premenopausal			Not provided
					Postmenopausal			0.3	0.1–0.9
John et al (2003)32	35–79	PCC	AA: 409/461 W: 449/499	Lifetime physical activity (since menarche) (hrs/week)
				Total activity
				Premenopausal	≥20.8 vs <9.1	0.76	0.36–1.61	0.68	0.35–1.34	X	X		X
				Postmenopausal	≥21.7 vs <9.6	0.91	0.60–1.41	0.71	0.47–1.07	X			X
				Total moderate activity
				Premenopausal	≥16.7 vs <6.8	0.44	0.20–0.99	0.77	0.38–1.56	X	X		X
				Postmenopausal	≥17.8 vs <7.6	1.02	0.66–1.59	0.60	0.40–0.92	X			X
				Recreational Activity
				Premenopausal	≥4.0 vs <1.5	0.79	0.39–1.60	1.37	0.73–2.55	X	X		X
				Postmenopausal	≥2.7 vs <0.7	1.13	0.76–1.70	1.04	0.69–1.57	X			X
				Total daily living activity
				Premenopausal	≥9.5 vs <4.0	0.71	0.30–1.67	0.81	0.38–1.73	X	X		X
				Postmenopausal	≥10.5 vs <4.3	1.10	0.71–1.71	0.91	0.58–1.44	X			X
				Mostly moderate or strenuous jobs
				Premenopausal	≥10.0 vs 0	0.87	0.40–1.91	0.67	0.35–1.28	X	X
				Postmenopausal	≥9.1 vs 0	0.62	0.39–1.00	0.77	0.51–1.16	X
Bernstein et al (2005)33	35–64	PCC	AA:1605/1646 W: 2933/3033	Lifetime exercise activity	Annual hrs/week ≥3.0 vs inactive	0.83	0.70–0.98	0.75	0.61–0.93
					Annual MET hrs/week ≥15.2 vs inactive	0.81	0.69–0.96	0.77	0.62–0.95	X
Ratnasinghe (2010)34		PCC	AA:88/406 W: 1463/2406	Physical activity						X	X
				time/wk	>3 vs <1	0.46	0.39–0.56	0.21	0.11–0.39
				min/time	>30 vs <10	0.51	0.42–0.62	0.27	0.14–0.52
				min/wk	>150 vs <30	0.55	0.46–0.67	0.25	0.14–0.52

Abbreviations: PC: prospective cohort; PCC: population based case-control study; W: White; AA: African American

Key Covariates: A: age; B: Body Mass Index; H: hormone use; R: reproductive factors (age at menarche, age at menopause, parity); X: adjusted for that covariate; P: partially adjusted for reproductive factors.