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Thyroid hormone levels and myogenesis of satellite cells. In quiescence, satellite cells are a heterogeneous population of multipotent, undifferentiated cells capable of auto-renewing. The TH signal is essential for the progression into terminal differentiation, while TH downregulation is required to retain muscle progenitor cells (mpcs) in a proliferative phase. The genes identified as T3 target during myogenesis are indicated.
