Table 1.
Dose level |
Drug | Dose (mg/m2) |
Drug | Dose | Drug | Dose (mg/m2) |
---|---|---|---|---|---|---|
−I | Paclitaxel IV | 135 | Carboplatin IP | AUC 6 | Paclitaxel IP | 60 |
I | Paclitaxel IV | 175 | Carboplatin IP | AUC 5 | Paclitaxel IP | 60 |
II | Paclitaxel IV | 175 | Carboplatin IP | AUC 6 | Paclitaxel IP | 60 |
III | Paclitaxel IV | 175 | Carboplatin IP | AUC 7 | Paclitaxel IP | 60 |
IVa | Paclitaxel IV | 135 | Carboplatin IP | AUC 6 | Paclitaxel IP | 60 |
In Dose Level IV, fixed dose bevacizumab 15 mg/kg IV was given cycles 2–6.