Table 1.
GOG protocols and study population.
| GOG protocol no. | Original study eligibility | Current study eligibility | Treatment regimen | No. of patients eligible |
|---|---|---|---|---|
| 114 | Optimal (≤ 1-cm residual), stage III EOC | Microscopic residual, stage III EOC | IV paclitaxel 135 mg/m2, cisplatin 75 mg/m2, × six cycles | 81 |
| 158 | Optimal (≤ 1-cm residual), stage III EOC | Microscopic residual, stage III EOC | IV paclitaxel 135 mg/m2, cisplatin 75 mg/m2, × six cycles or IV paclitaxel 175 mg/m2(3 h), carboplatin AUC 7.5, × six cycles | 281 |
| 172 | Optimal (≤ 1-cm residual), stage III EOC/PPC | Microscopic residual, stage III EOC | IV paclitaxel 135 mg/m2, cisplatin 75 mg/m2, × six cycles | 75 |
Abbreviations: GOG, Gynecologic Oncology Group; EOC, epithelial ovarian cancer; IV, intravenously; AUC, area under the curve; PPC, primary peritoneal carcinoma.