Table II.
Biochemical properties of self-assembled neocartilage*
| Groups | Collagen/WW % (P < 0.0001) |
GAG/WW % (P = 0.718) |
PYR/WW (nmol/g) (P = 0.0036) |
PYR/Col (nmol/mg) (P < 0.0001) |
|---|---|---|---|---|
| Control | 3.03 ± 0.61A | 4.39 ± 2.10 | 4.99 ± 1.86B | 0.16 ± 0.030D |
| 1st & 3rd weeks | 1.93 ± 1.27B | 3.84 ± 3.85 | 5.68 ± 1.00A,B | 0.30 ± 0.169A |
| 3rd & 4th weeks | 3.33 ± 1.23A | 4.96 ± 3.44 | 6.63 ± 1.90A | 0.20 ± 0.034C |
| 4th week | 3.03 ± 1.50A | 4.91 ± 3.50 | 5.19 ± 1.06B | 0.17 ± 0.105C,D |
| Continuous | 1.91 ± 0.44B | 4.44 ± 2.96 | 5.08 ± 1.88B | 0.26 ± 0.063B |
Biochemical properties of the engineered neocartilage as represented by Col/WW, GAG/WW, PYR/WW and PYR/Col. Values are mean ± 95% CI. Fisher’s post hoc testing was applied if P < 0.05. Groups not connected by the same letter are significantly different. See Results section for details. Col = collagen.