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. Author manuscript; available in PMC: 2014 Jun 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2013 Apr 6;269(3):263–269. doi: 10.1016/j.taap.2013.03.025

Table 1.

Comparison of transsulfuration metabolites in cerebellum between control and TCE-treated mice.

Glutathione and Cysteine Redox Status in cerebellum (nmol/mg/protein) 0 mg/ml TCE 0.01 mg/ml TCE 0.1 mg/ml TCE
GSH 22.22 ± 1.53 19.58 ± 0.87* 17.92 ± 1.21**
GSSG 0.27 ± 0.05 0.27 ± 0.03 0.29 ± 0.04
GSH/GSSG ratio 86.36 ± 18.46 71.76 ± 7.11 63.14 ± 7.11*
Oxidized GSH (%) 2.33 ± 0.50 2.73 ± 0.27 3.09 ± 0.39*
Cysteine 3.20 ± 0.44 2.51 ± 0.54 2.39 ± 0.76
Cystine 12.52 ± 1.23 14.38 ± 1.87 14.64 ± 0.79*
Cysteine/Cystine ratio 0.26 ± 0.03 0.18 ± 0.05* 0.16 ± 0.04*

Data is presented as mean ± SD.

*

p≤0.05 is statistically significant

**

p<0.001.