Table 1.
Characteristics of the study subjects
| Mean ± SE (unless otherwise noted) | |
|---|---|
| Demographics | |
| Age (years) | 47.5 ± 2.5 |
| Gender (male) | 12/12 (100%) |
| Immune parameters | |
| Duration HIV (years) | 14.1 ± 1.5 |
| Duration ART (years) | 9.2 ± 1.7 |
| NRTI (years) | 9.0 ± 1.6 |
| NNRTI (years) | 1.7 ± 0.9 |
| PI (years) | 7.7 ± 2.1 |
| NRTI | |
| current | 11/12 (92%) |
| past | 1/12 (8%) |
| never | 0/12 (0%) |
| NNRTI | |
| current | 2/12 (17%) |
| past | 3/12 (25%) |
| never | 7/12 (58%) |
| PI | |
| current | 5/12 (42%) |
| past | 3/12 (25%) |
| never | 4/12 (33%) |
| CD4 count (#/mm3) | 536 ± 46 |
| viral load (undetectable) | 12/12 (100%) |
| TNF-α (pg/mL) | 13 ± 3 |
| Body composition parameters | |
| BMI (kg/m2) | 23.7 ± 1.4 |
| iliac waist circumference (cm) | 87 ± 3 |
| abdominal subcutaneous adipose tissue (cm) by CT | 131 ± 24 |
| visceral adipose tissue (cm) by CT | 100 ± 21 |
| arm fat (kg) by DXA | 0.9 ± 0.1 |
| leg fat (kg) by DXA | 1.7 ± 0.2 |
| fat percentage of extremities by DXA | 16.5 ± 1.9 (range 8.2 – 27.9%) |
| Metabolic parameters | |
| Total cholesterol (mmol/l) | 4.4 ± 0.2 |
| LDL cholesterol (mmol/l) | 2.5 ± 0.2 |
| HDL cholesterol (mmol/l) | 1.2 ± 0.1 |
| Triglycerides (mmol/l) | 1.5 ± 0.3 |
| Fasting glucose (mmol/l) | 4.6 ± 0.2 |
| HOMA-IR | 0.8 ± 0.2 (range 0.1 – 3.1) |