Table 1.
Characteristics of First Kidney Transplant Recipients, by Presence of Atrial Fibrillation
| All N = 62,706 |
No Atrial Fibrillation N=58,912 |
Atrial Fibrillation N=3,794 |
P-value1 | |
|---|---|---|---|---|
| Patient Demographics | ||||
| Patient age | 51 (40–61) | 50 (39–60) | 60 (52–67) | <0.001 |
| Female | 39.3 | 39.8 | 31.2 | <0.001 |
| Race2 | ||||
| White | 57.5 | 56.7 | 70.3 | <0.001 |
| Black | 34.8 | 35.5 | 23.9 | |
| Other | 7.7 | 7.8 | 5.7 | |
| BMI at transplant (kg/m2) | ||||
| < 20 | 2.0 | 2.0 | 1.6 | <0.001 |
| 20– 25 | 27.7 | 28.0 | 23.6 | |
| 26–30 | 26.7 | 26.6 | 29.1 | |
| >30 | 22.9 | 22.6 | 27.0 | |
| Missing | 20.7 | 20.8 | 18.8 | |
| Cause of ESRD | ||||
| Diabetes | 31.6 | 31.4 | 33.9 | <0.001 |
| Hypertension | 24.3 | 24.2 | 25.4 | |
| Glomerulonephritis | 25.0 | 25.2 | 21.1 | |
| Other | 18.2 | 18.1 | 18.6 | |
| Missing | 1.0 | 1.0 | 1.1 | |
| Dialysis Vintage (years) | ||||
| < 2.5 years | 26.2 | 26.1 | 26.7 | 0.01 |
| 2.5 – 5 years | 43.6 | 43.7 | 41.4 | |
| > 5 years | 30.3 | 30.1 | 31.9 | |
| Dialysis Modality | ||||
| Hemodialysis | 85.7 | 85.4 | 90.9 | <0.001 |
| Peritoneal Dialysis | 14.2 | 14.5 | 8.9 | |
| Missing | 0.2 | 0.2 | 0.2 | |
| Skilled Nursing Facility Utilization | 2.5 | 2.2 | 7.0 | <0.001 |
| Hospital days (N) | 4 (2–10) | 4 (2–9) | 10 (4–20) | <0.001 |
| Non-nephrology clinic visits (N) | 18 (9–30) | 17 (9–29) | 27 (16–42) | <0.001 |
| Comorbidities | ||||
| Diabetes | 42.3 | 39.3 | 49.0 | <0.001 |
| Cancer | 3.7 | 3.3 | 6.0 | <0.001 |
| Coronary artery disease | 11.8 | 9.2 | 24.0 | <0.001 |
| Cerebrovascular disease | 8.4 | 7.2 | 16.2 | <0.001 |
| Cerebral hemorrhage | 0.5 | 0.5 | 1.2 | <0.001 |
| Alcohol | 1.1 | 0.8 | 1.0 | 0.12 |
| Tobacco | 6.3 | 4.5 | 5.0 | 0.23 |
| PVD | 16.6 | 13.6 | 26.6 | <0.001 |
| Hypertension | 95.4 | 80.5 | 95.0 | <0.001 |
| Valve disease | 12.6 | 9.7 | 29.8 | <0.001 |
| Heart failure | 22.8 | 18.1 | 44.9 | <0.001 |
| Chronic pulmonary disease | 13.0 | 10.3 | 22.9 | <0.001 |
| Previous Solid Organ Transplant | ||||
| Heart transplant | 0.6 | 0.6 | 1.0 | <0.001 |
| Lung transplant | 0.1 | 0.1 | 0.4 | <0.001 |
| Liver transplant | 0.9 | 0.8 | 1.5 | <0.001 |
| Pancreas transplant | 0.4 | 0.4 | 0.2 | 0.03 |
| Patient blood type | ||||
| O | 48.5 | 48.6 | 45.7 | <0.001 |
| A | 33.0 | 32.8 | 37.1 | |
| B | 14.6 | 14.7 | 13.0 | |
| AB | 3.8 | 3.7 | 4.1 | |
| Missing | 0.1 | 0.1 | 0.1 | |
| Panel reactive antibody | ||||
| 0–10% | 65.2 | 65.2 | 67.5 | 0.001 |
| 11–80% | 18.6 | 18.6 | 18.3 | |
| >80% | 6.3 | 6.3 | 6.0 | |
| Missing | 9.9 | 10.0 | 8.2 | |
| Transplant Characteristics | ||||
| Donor age | 39 (24–51) | 39 (24–50) | 43 (28–53) | <0.001 |
| Missing | 7.2 | 7.2 | 6.1 | |
| Donor Gender | ||||
| Female | 43.5 | 43.4 | 44.7 | 0.03 |
| Missing | 0.2 | 0.2 | 0.1 | |
| Transplant type | ||||
| Living donor | 16.6 | 16.5 | 17.6 | <0.001 |
| Standard deceased donor | 62.5 | 62.7 | 58.2 | |
| Expanded criteria donor | 8.6 | 8.4 | 11.7 | |
| Donation after cardiac death | 5.3 | 5.2 | 6.6 | |
| Missing | 7.2 | 7.3 | 5.9 | |
| Number HLA mismatches | ||||
| 0 | 8.7 | 8.6 | 10.0 | <0.001 |
| 1–3 | 26.2 | 26.2 | 25.6 | |
| 4–6 | 59.0 | 58.9 | 60.2 | |
| Missing | 6.1 | 6.3 | 4.3 | |
| Cold ischemia time (hours) | ||||
| <10 | 20.2 | 20.1 | 21.0 | <0.001 |
| 10 – 23 | 41.0 | 41.0 | 40.7 | |
| > 23 | 21.9 | 21.8 | 23.5 | |
| Missing | 17.0 | 17.1 | 14.8 | |
All values are presented as percent or median (interquartile range).
1
p-values based on Chi-square tests for categorical variables and Kolmogorov-Smirnov test for continuous variables.
2
Fourteen patients had missing race all belonging to the No Atrial Fibrillation group.