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. 2013 Jun 3;8(6):e64647. doi: 10.1371/journal.pone.0064647

Figure 5. Effect of CXCR2 and KC bone marrow chimeras on the progression of GLD.

Figure 5

The survival of Twitcher mice transplanted with CXCR2-deficient bone marrow (green, GALC+/+CXCR2−/− to Twitcher) or KC−/−GALC−/− mice transplanted with wild type bone marrow (black, wildtype to KC−/−GALC−/−) is not significantly different from Twitcher mice receiving wild type bone marrow (blue, wildtype to twitcher) (A). Twitcher mice transplanted with Twitcher bone marrow (red, Twitcher to Twitcher) have a similar survival (median age = 45 days) compared to untransplanted Twitcher mice (data not shown). The weights of various bone marrow chimeras are not significantly different from each other, but are significantly decreased compared to the wild type controls (B).