Table 2. Clinical characteristics of the 93 travelers with dengue.

		%	N
Clinical symptoms
Fever		93	86/92
Rash		71	65/92
Headache		64	59/92
Myalgia		55	51/92
Fatigue		51	47/92
Other gastrointestinal symptoms		46	42/92
Nausea		45	41/92
Arthralgia		34	31/92
Respiratory symptoms		27	25/92
Hemorrhagic manifestations		24	22/92
Vomiting		24	22/92
Retro-orbital pain		17	16/92
Pruritus		9	8/90
Shock		0	0/92
Routine laboratory findings in follow-upa
Anaemia (<134/117 g/L)		9	5/56
Elevated Hb (>167/155 g/L)		13	11/87
Low Hcr (<39%/35%)		9	5/56
Elevated Hcr (>50%/46%)		8	7/87
Leukopenia (<3.4×109/L)		67	59/88
Thrombocytopenia (<150×109/L)		78	68/87
Elevated AST (>45/35 U/L)		78	49/63
Elevated ALT (>70/45 U/L)		61	51/83
Elevated creatinine (>100/90 µmol/L)		25	10/40
Patients positive for the various diagnostic testsb
PCR		74%	67/90
NS1		79%	72/91
IgMc		100%	93/93
IgG		98%	91/93
Serotype identified
DENV-1		26	24/93
DENV-2		8	7/93
DENV-3		24	22/93
DENV-4		3	3/93
Not known		40	37/93
Co-infectionsd
At least one co-infection		19	17e/91
Gastrointestinal infection		9	8/91
Respiratory tract infection		4	4/91
Urinary tract infection		2	2/91
Other bacterial disease		2	2/91
Malaria		2	2/91
Other parasitic disease		1	1/91
Hospitalization		79	73f/92

^aReference values for males/females in parentheses.

^bAt least once during the 21 days since illness onset. The timing of serum sampling was not standardized.

^cSelection criterion for entering the study.

^dDiagnosed according to current practice.

^eOf these patients, 9/17 (53%) were positive for PCR or NS1 at some point. The patients negative for PCR and NS1 provided samples on illness days 6–21.

^fDuration of hospitalization: median 4 days, interquartile range 3 to 6 days.

Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; DENV, dengue virus; Hb, hemoglobin; Hcr, hematocrit.