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| Fluoroquinolone | Mol. Weight | ClogP | PSA | % Decrease |
| Ciprofloxacin | 331.35 | −0.725 | 77.04 | 69% |
| Moxifloxacin | 437.9 | −0.082 | 86.27 | 49% |
| Ofloxacin | 361.4 | −0.508 | 77.48 | 58% |
| Gatifloxacin | 375.4 | −0.266 | 86.27 | 31% |
Molecular weights, Partition Coefficients (ClogP), Polar Surface Areas (PSA) and relative spermidine-induced reductions in intracellular accumulation of four fluoroquinolones (as illustrated in Figure 3A).
