. Author manuscript; available in PMC: 2014 Jan 1.

Published in final edited form as: Arthritis Rheum. 2013 Jan;65(1):211–215. doi: 10.1002/art.37751

Table 2.

VKORC1 in replication cohort with adjustment for ancestry and stratification by ethnic subgroup

Analysis	SNP	Case/Control	Case	Control	P	OR (95%CI)
All subjects adjusted for PC1, PC2, PC3	rs9934438	1496/993	0.136	0.093	0.0029^†	1.34 (1.11–1.62)
All subjects adjusted for PC1, PC2, PC3	rs9923231	1496/993	0.135	0.093	0.0032^†	1.34 (1.10–1.62)
Chinese subgroup	rs9934438	1022/809	0.123	0.099	0.020^‡	1.28 (1.04–1.58)
Chinese subgroup	rs9923231	1022/809	0.122	0.099	0.028^‡	1.27 (1.03–1.56)
Korean/Japanese subgroup	rs9934438	260/67	0.102	0.052	0.076^‡	2.06 (0.91–4.64)
Korean/Japanese subgroup	rs9923231	260/67	0.102	0.045	0.043^‡	2.38 (1.00–5.67)
Southeast Asian subgroup	rs9934438	112/7	0.290	0.071	0.076^‡	5.31(0.68–41.46)
Southeast Asian subgroup	rs9923231	112/7	0.290	0.071	0.076^‡	5.31 (0.68–41.46)

^†

By logistic regression with first three principal components derived from Immunochip markers as covariates.

^‡

By chi-square test.