Table 1.
LCL cell administration (n)1 | No. with tumor (time of analysis)2 | No. with hCD47-LCL / No. with pKS-LCL3 |
---|---|---|
Peritoneal Cavity (12) | 5 (17, 21, 31, 35, 45) | 5/0 |
Kidney capsule (5) | 4 (14, 21, 35, 35) | 4/0 |
A mixture (1:1) of hCD47-LCL and pKS-LCL cells (total 5×107 cells/mouse) were injected into peritoneal cavity (n=12) or renal subcapsular space (n=5).
Number of mice with visible tumor at sacrifice (days after LCL cell administration).
Number of mice with hCD47-LCL (human CD47+) and pKS-LCL (human CD47−) tumor cells determined by flow cytometric analysis of tumor cell suspensions using anti-human CD47 mAb.