TABLE II.
Impact of primary granulocyte colony–stimulating factor prophylaxis on chemotherapy dose intensity
| Relative dose intensity |
Patient group
|
p Valuea | ||
|---|---|---|---|---|
| Overall | Primary g-csf prophylaxis | |||
| Yes | No | |||
| Received fec/d regimen (n) | 211 | 124 | 87 | |
| Mean (%) | 97 | 98 | 95 | 0.005 |
| Range (%) | 60–117 | 75–117 | 60–100 | |
| ≥85% [n (%)] | 200 (95) | 120 (97) | 80 (92) | 0.118 |
| <85% [n (%)] | 11 (5) | 4 (3) | 7 (8) | |
a
Based on the Mann–Whitney U-test (continuous data) or the Fisher exact chi-square test.
g-csf = granulocyte colony–stimulating factor; fec/d = 5-fluorouracil–epirubicin–cyclophosphamide followed by docetaxel.