Table 1.
DAA | HCV genotype | Course of DAA (wk) | Course of therapy (wk) | Dose | With or without pegIFN-α | Published year | Ref. |
Telaprevir | 1a/1b/1c/unknown | 12/8 | 20/24/44/48 | 750 mg (tid) | With | 2011 | [30-32] |
Boceprevir | 1a/1b/unknown | 24/32/44 | 28/36/48 | 800 mg (tid) | With | 2011 | [33-34] |
Daclatasvir | 1a/1b | 24 | 24 | 60 mg (qd) | With or without | 2012 | [36] |
Asunaprevir | 1a/1b | 24 | 24 | 600 mg (bid) | With or without | 2012 | [36] |
Sofosbuvir | 1/2/3 | 8/12 | 8/12 | 400 mg (qd) | Without | 2013 | [37] |
ABT-450 | 1a/1b | 12 | 12 | 250/150 mg (qd) | Without | 2013 | [38] |
qd: Once daily; bid: Twice daily; tid: Thrice daily; DAA: Direct acting antiviral agent; HCV: Hepatitis C virus; pegIFN-α: Peginterferon-α.