Table 5. Radiation morbidity.
| |
Radical hysterectomy (n=66) |
Neoadjuvant chemotherapy (n=67) |
||||
|---|---|---|---|---|---|---|
| Grade 3 | Grade 4 | Grade 3 or 4 (%) | Grade 3 | Grade 4 | Grade 3 or 4 (%) | |
|
Early adverse events | ||||||
| Leukocytes | 0 | 0 | 0 | 1 | 0 | 1 |
| Haemoglobin | 0 | 0 | 0 | 2 | 1 | 4 |
| Thrombocytes | 0 | 0 | 0 | 1 | 0 | 1 |
| Diarrhoea | 5 | 0 | 8 | 2 | 0 | 3 |
| Nausea | 0 | — | 0 | 1 | — | 1 |
| Vomiting | 0 | 0 | 0 | 1 | 0 | 1 |
| Lymphedema | 1 | 0 | 2 | 0 | 0 | 0 |
| Dysuria | 1 | — | 2 | 0 | — | 0 |
| Urinary retention |
9 |
0 |
14 |
5 |
0 |
7 |
|
Late adverse eventsa | ||||||
| Lymphedema | 2 | 0 | 3 | 5 | 0 | 7 |
| Urinary retention | 7 | 0 | 11 | 3 | 1 | 6 |
| Vesicovaginal fistula | 1 | 0 | 2 | 1 | 1 | 3 |
| Bowel obstruction | 6 | 0 | 9 | 1 | 2 | 4 |
a
Late adverse events were defined as the adverse events that were observed more than 90 days after radiation therapy.