. 2012 Oct 30;24(6):1033–1038. doi: 10.1007/s00192-012-1970-1

Table 4.

Genotype combinations of the position −1607/−1608 MMP-1 polymorphism and the position −1612/−1617 MMP-3 polymorphism

Control group, freq. of polymorphisms (%)		MMP-3
Control group, freq. of polymorphisms (%)		5A/5A	5A/6A	6A/6A
MMP-1	1G/1G	39.5	58.1	2.3
	1G/2G	26.4	56.6	17
	2G/2G	6.2	68.7	25
Study group, freq. of polymorphisms (%)
MMP-1	1G/1G	39.5	51.2	9.3^b
	1G/2G	14^a	68^b	18
	2G/2G	10.3^b	75.9^b	13.8^a

The results are the observed frequencies of the study (POP) patients and controls. Pearson’s Chi squared test = 28.6, p = 0.005,

^aSNPs underrepresented in the study group

^bSNPs overrepresented in the study group