Table 1.
Patient characteristics of 105 patients with invasive fungal infection (IFI) in the intensive care unit (ICU)
| Characteristics | Yeast infection, n = 92 | Mold infection, n = 13 |
|---|---|---|
| Age (years), median (IQR) | 60 (43.25–61.75) | 59.5 (48.25–69) |
| Male sex, n (%) | 58 (63.0) | 9 (69.2) |
| Comorbidities, n (%) | 17 (18.5) | 11 (84.6)* |
| COPD | 6 | 6 |
| Diabetes | 11 | 5 |
| Hematological malignancy, n (%) | 0 | 5 (38.5)* |
| Solid tumor, n (%) | 14 (15.2) | 3 (23.1) |
| Steroid therapy, n (%) | 15 (16.3) | 10 (76.9)* |
| Previous hospitalization, n (%) | 33 (35.9) | 7 (53.8) |
| Admission typology n (%) | ||
| Surgical pathology | 33 (35.9) | 2 (15.4) |
| Medical pathology | 33 (35.9) | 10 (76.9)* |
| Trauma | 26 (28.2) | 1 (7.7) |
| Pre-IFI diagnosis LOS (days), median (IQR) | 20 (10–39.25) | 25 (16.25–41.75) |
| SOFA score on IFI diagnosis, median (IQR) | 7 (6–8) | 7 (6–8) |
| Antifungals, n (%) | ||
| Prophylaxis | 18 (19.6) | 0 |
| Empirical | 16 (17.4) | 0 |
| Mortality (end of follow up), n (%) | 37 (40.2) | 8 (61.5) |
IQR interquartile range, COPD chronic obstructive pulmonary disease, LOS length of stay, SOFA Sequential Organ Failure Assessment
* Statistically significant p-value (<0.05)