Table 3.
The neuropathologically investigated group - diagnoses and individual levels of CSF markers
| Case | Aβ42 (ng/L) | Tau (ng/L) | P-tau (ng/L) | NFL (ng/L) | Clinical diagnosis | Neuropathological diagnosis | Degeneration severity | Dementia duration at LP (years) | Age at death (years) | Brain weight (g) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
726 |
819 |
NA |
5546 |
FTD |
FTD-TDP43 |
moderate |
2 |
54 |
1020 |
| 2 |
570 |
410 |
35 |
3770 |
FTD-MND |
FTD-TDP43 |
mild |
0.4 |
62 |
1600 |
| 3 |
420 |
620 |
NA |
2600 |
bvFTD |
FTD-FUS |
severe |
3 |
37 |
NK |
| 4 |
500 |
450 |
54 |
1620 |
bvFTD |
FTD-TDP43 |
severe |
NK |
67 |
1340 |
| 5 |
662 |
494 |
NA |
1494 |
bvFTD |
FTD-FUS |
severe |
3 |
34 |
NK |
| 6 |
411 |
263 |
NA |
1241 |
FTD(PPA) |
FTD-TDP43 |
severe |
12 |
76 |
975 |
| 7 |
370 |
330 |
29 |
1050 |
FTD(PPA) |
FTD-TDP43 |
severe |
5 |
69 |
760 |
| 8 |
780 |
490 |
68 |
1030 |
bvFTD |
FTD-tau |
mild |
4 |
81 |
1125 |
| 9 |
369 |
554 |
95 |
665 |
FTD(PPA) |
FTD-tau |
severe |
7 |
73 |
1010 |
| 10 | 639 | 528 | NA | <250 | AD | FTD-tau | mild | NK | 53 | 1335 |
PPA Primary progressive aphasia.
NA Not analysed.
NK Not known.