Table 5.
Expression levels of integrins genes in relation to clinicopathological variables and immunohistochemical scores (p < 0.05)
| Integrin | Gene expression - group | Protein expression - group | Validation |
|---|---|---|---|
| α6 |
Over - vascular invasion + |
Over - vascular invasion + |
Yes |
| Over - mucinous |
No |
||
| Over - TNM III,IV |
No |
||
| αV |
Over - neural invasion + |
Over - neural invasion + |
Yes |
| Over - TNM III,IV |
No |
||
| Over - vascular invasion + |
No |
||
| α5 |
Over – mucinous |
Over - mucinous |
Yes |
| Under - age >60 |
Over – age >60 |
No |
|
| β5 |
Over - TNM III |
Over - TNM III,IV |
Yes |
| α3 | Over - TNM III | Over - TNM III,IV |
Yes |
| Over- vascular invasion + | No |