Table 3.
Side effects
| Placebo | Alfentanil | P value | |
|---|---|---|---|
| Nausea |
2.2 (1/45) |
6.7 (3/45) |
0.62 |
| Vomiting |
0.0 (0/45) |
2.2 (1/45) |
1.00 |
| Dry mouth |
2.2 (1/45) |
0.0 (0/45) |
1.00 |
| Blurry vision |
4.4 (2/45) |
2.2 (1/45) |
1.00 |
| Dizziness |
4.4 (2/45) |
37.8 (17/45) |
<0.001 |
| Sleepy |
0.0 (0/45) |
2.2 (1/45) |
1.00 |
| Dyspnoeic |
0.0 (0/45) |
2.2 (1/45) |
1.00 |
| Sweating |
0.0 (0/45) |
2.2 (1/45) |
1.00 |
| Pressure sensation |
0.0 (0/45) |
2.2 (1/45) |
1.00 |
| Desaturation (SpO2 < 90%) * |
8.1 (3/37) |
44.4 (16/36) |
<0.001 |
| Desaturation >15 seconds (SpO2 < 90%) |
8.1 (3/37) |
19.4 (7/36) |
0.19 |
| Desaturation (SpO2 < 85%) # |
2.7 (1/37) |
16.7 (6/36) |
0.06 |
| Desaturation >15 seconds (SpO2 < 85%) # |
0.0 (0/37) |
0.0 (0/36) |
1.00 |
| Irregular heart rhythm |
18.9 (7/37) |
16.7 (6/36) |
1.00 |
| Systolic blood pressure at 5 minutes (20% decrease) |
8.9 (4/45) |
11.1 (5/45) |
1.00 |
| Diastolic blood pressure at 5 minutes (20% decrease) |
20.0 (9/45) |
15.6 (7/45) |
0.78 |
| Heart rate at 5 minutes (20% decrease) | 4.4 (2/45) | 0.0 (0/45) | 0.49 |
This table shows the percentage of patients with different side effects for the placebo and alfentanil group.
* All > 15 sec and < 85% desaturations are also counted for this category.
# All < 85% saturations lasted 2–9 seconds, on average 4.2 seconds.