Table 3.
Univariate and mutivariate analysis for survival
| Variable |
Univariate analysis |
Mutivariate analysis |
||||
|---|---|---|---|---|---|---|
| CHR | 95% CI | P | CHR | 95% CI | P | |
| Gender | ||||||
| Female |
1 |
|
|
1 |
|
|
| Male |
0.70 |
1.18-2.44 |
0.004 |
1.44 |
1.00-2.08 |
0.049 |
| Age | ||||||
| < 65 |
1 |
|
|
1 |
|
|
| ≥65 |
1.26 |
1.02-1.56 |
0.031 |
1.17 |
0.93-1.46 |
0.175 |
| Tumor length | ||||||
| < 5cm |
1 |
|
|
1 |
|
|
| ≥5cm |
1.01 |
0.84-1.22 |
0.897 |
0.95 |
0.79-1.15 |
0.618 |
| pT-category | ||||||
| T1-2 |
1 |
|
|
1 |
|
|
| T3 |
1.42 |
1.09-1.87 |
0.011 |
1.48 |
1.12-1.95 |
0.005 |
| T4 |
2.65 |
1.82-3.87 |
< 0.001 |
2.27 |
1.53-3.35 |
<0.001 |
| pN-category | ||||||
| N1 |
1 |
|
|
1 |
|
|
| N2 |
1.39 |
1.12-1.74 |
0.003 |
1.33 |
1.06-1.67 |
0.015 |
| N3 |
2.70 |
2.14-3.40 |
< 0.001 |
1.79 |
1.29-2.48 |
< 0.001 |
| LNMR | ||||||
| < 0.25 |
1 |
|
|
1 |
|
|
| ≥0.25 |
2.36 |
1.91-2.91 |
< 0.001 |
1.54 |
1.14-2.07 |
0.004 |
| Tumor differentiation | ||||||
| High (G1) |
1 |
|
|
1 |
|
|
| Moderate (G2) |
0.88 |
0.66-1.17 |
0.383 |
0.88 |
0.67-1.19 |
0.423 |
| Low (G3) |
1.13 |
0.82-1.56 |
0.463 |
0.94 |
0.67-1.30 |
0.689 |
| PORT | ||||||
| No |
1 |
|
|
1 |
|
|
| Yes |
0.79 |
0.65-0.97 |
0.018 |
0.77 |
0.63-0.94 |
0.001 |
| POCT | ||||||
| No |
1 |
|
|
1 |
|
|
| Yes | 1.10 | 0.91-1.33 | 0.325 | 1.15 | 0.91-1.44 | 0.061 |
CHR, Cox hazard ratio; 95% CI, 95% Confidence Interval; LNMR, lymph-node metastatic ratio; PORT, postoperative radiation therapy; POCT, postoperative chemotherapy.