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The experiment design and theoretic digestion result. (a) The serum of SILAC mouse was mixed with serum and urine from human, and then enzyme digestion was performed. The shared digested peptides between human and mouse could be selected as SILAC pair and quantified. (b) The comparison of molecular weight distribution for the theoretic digestion peptides of trypsin and Lys-C. (c) The comparison of Lys-C theoretic digestion peptides in human and mouse database.
