Table 1.
The significant proteins associated with nephropathy.
| Peptide sequence | Protein name | Fold changes treated : untreated | Relevance with nephropathy | Reference |
|---|---|---|---|---|
| ACEPGVDYVYK | Complement C3 | −3.3 | Reported as a potentially novel predictor of progressive IgA nephropathy | [19] |
|
| ||||
| HEVTGWVLVSPLSK | Insulin-like growth factor-binding protein 7 | −3.2 | The urinary levels of other IGFBPs correlated with the development of renal disease | [20] |
|
| ||||
| VHTECCHGDLLECADDRADLAK | Albumin | −2.3 | Most famous indicator for nephropathy | [21, 22] |
| YICENQDSISSKLK | −2.0 | |||
| AEFAEVSK | −1.9 | |||
| AAFTECCQAADKAACLLPK | −1.6 | |||
|
| ||||
| HQPQEFPTYVEPTNDEICEAFRK | Vitamin D-binding protein isoform 3 | −2.1 | Enhanced excretion in urine during diabetic nephropathy | [23] |
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| ||||
| DSGRDYVSQFEGSALGK | Apolipoprotein A-I | −2.1 | Increased in the plasma of diabetic nephropathy patients | [24] |
|
| ||||
| HYYIGIIETTWDYASDHGEK | Ceruloplasmin | −1.7 | Enhanced excretion in urine during diabetic nephropathy | [25, 26] |
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| SSFVAPLEK | Pigment epithelium-derived factor | −1.6 | A urinary marker for diabetic nephropathy | [27] |
|
| ||||
| DSAHGFLK | Transferrin | −1.6 | Enhanced excretion in urine during diabetic nephropathy | [22, 28] |