Table 1.
Study groups and their interventions.
| Groups | Model | Administration (timing) |
|---|---|---|
| Sham-control (n = 6) | Sham operation | Distilled water 1 mL as vehicle (6 hrs after operation) |
| Sepsis-control (n = 6) | CLP | Distilled water 1 mL as vehicle (6 hrs after CLP) |
| CLP + BHT-L6 (0.45 g/kg) (n = 6) | CLP | BHT 0.5 mL + distilled 0.5 mL (6 hrs after CLP) |
| CLP + BHT-H6 (0.9 g/kg) (n = 6) | CLP | BHT 1 mL (6 hrs after CLP) |
| CLP + BHT-L12 (0.45 g/kg) (n = 6) | CLP | BHT 0.5 mL + distilled 0.5 mL (12 hrs after CLP) |
| CLP + BHT-H12 (0.9 g/kg) (n = 6) | CLP | BHT 1 mL (12 hrs after CLP) |
CLP: rats received cecal ligation and puncture.
BHT-L6: low dose of BHT was orally administered 6 hrs postoperatively.
BHT-H6: high dose of BHT was orally administered 6 hrs postoperatively.
BHT-L12: low dose of BHT was orally administered 12 hrs postoperatively.
BHT-H12: high dose of BHT was orally administered 12 hrs postoperatively.