Table 2.

HAdV quantification studies in environmental water matrices.

Authors [Reference]	qPCR detection method [Reference]	Matrices analyzed	Main results
He and Jiang, 2005 [32]	He and Jiang, 2005 [32]	Sewage and coastal waters	Mean values in sewage 8.1E + 05 GC/L. Serotypes 1–5, 9, 16, 17, 19, 21, 28, 37, 40, 41
Choi and Jiang, 2005 [33]	He and Jiang, 2005 [32]	River	2–4 logs GC/L, 16% positive samples
Haramoto et al., 2005 [34]	Heim et al., 2003 [35]	River	45% positive samples (29/64)
Albinana-Gimenez et al., 2006 [36]	Hernroth et al., 2002 [26]	River and sewage	River used as a source of water presented 4E + 02 GC/L
Bofill-Mas et al., 2006 [37]	Hernroth et al., 2002 [26]	Sewage, effluent, and biosolids	High HAdV quantities in sewage, effluent, and biosolids. t90 and t99 of 60.9 and 132.3 days
Calgua et al., 2008 [38]	Hernroth et al., 2002 [26]	Seawater	New skimmed-milk flocculation method to concentrate, mean values of 1.26E + 03 GC/L
Albinana-Gimenez et al., 2009 [39]	Hernroth et al., 2002 [26]	River and drinking-water treatment plants	90% positive for river water, mean values 1E + 01–1E + 04 GC/L
Dong et al., 2010 [40]	Heim et al., 2003 [35], and by Ko et al., 2005 [41]	Sewage, drinking water, and river and recreational waters	Adenovirus detected from all water types. 10/10 positives in sewage (1.87E + 03–4.6E + 06 GC/L), 5/6 positives in recreational waters (1.70E + 01–1.19E + 03 GC/L)
Hamza et al., 2009 [42]	Heim et al., 2003 [35]	River and sewage	97.5% positive river water samples (1.0E + 07–1.7E + 08 GC/L)
Ogorzaly et al., 2009 [43]	Hernroth et al., 2002 [26]	River	100% positive samples (1.0E + 04/l)
Bofill-Mas et al., 2010 [44]	Hernroth et al., 2002 [26]	Seawater	3.2E + 03 GC/L, HAdV41 the most prevalent
Haramoto et al., 2010 [45]	Ko et al., 2005 [41]	River water	HAdV more prevalent (61.1%) than JCPyV (11.1%)
Jurzik et al., 2010 [46]	Heim et al., 2003 [35]	Surface waters	96.3% positive samples (mean 2.9E + 03 GC/L and maximum of 7.3E + 05 GC/L)
Ogorzaly et al., 2010 [47]	Hernroth et al., 2002 [26]	Groundwater	HAdV was the most stable between MS2 and GA phages analyzed in groundwater
Rigotto et al., 2010 [48]	Hernroth et al., 2002 [26]	Seawater, lagoon brackish water, sewage, and drinking water	64.2% positive values (54/84)
Schlindwein et al., 2010 [49]	Hernroth et al., 2002 [26]	Sewage, effluent, and sludge	4.6E + 07–1.2E + 09 GC/L in sludge, 5E + 04–1.3E + 07 GC/L in sewage, and 3.1E + 05–5.4E + 05 GC/L in effluent
Aslan et al., 2011 [50]	Xagoraraki et al., 2007 [51]	Surface waters	2–4 logs GC/L, 36% positives (HAdV 40/41)
Calgua et al., 2011 [52]	Hernroth et al., 2002 [26]	Seawater	Mean values 1–3 logs GC/L
Guerrero-Latorre et al., 2011 [53]	Hernroth et al., 2002 [26]	River and groundwater	Low levels of HAdV in 4/16 groundwater samples
Hamza et al., 2011 [54]	Heim et al., 2003 [35]	River and sewage	3E + 03 GC/L in river and 1.0E + 07–1.7E + 08 GC/L in sewage
Kokkinos et al., 2011 [55]	Hernroth et al., 2002 [26]	Sewage	45.8% positive samples (22/48) in sewage. Main serotypes 8, 40, and 41
Souza et al., 2011 [56]	Hernroth et al., 2002 [26]	Seawater	HAdV as the most prevalent in seawater
Wong and Xagoraraki, 2011 [57]	Heim et al., 2003 [35]	Manure and sewage sludge	Concentrations of E. coli and Enterococcus correlate to HAdV (P ≥ 0.05) in sludge samples
Wyn-Jones et al., 2011 [58]	Hernroth et al., 2002 [26]	Recreational water	36.4% positive samples, more prevalent than noroviruses (9.4%)
Garcia et al., 2012 [59]	Hernroth et al., 2002 [26]	River (source water)	100% prevalence (1E + 07 GC/L)
Fongaro et al., 2012 [60]	Hernroth et al., 2002 [26]	Lagoon	96% positive samples (46/48)
Rodriguez-Manzano et al., 2012 [13]	Hernroth et al., 2002 [26]	Raw sewage, secondary and terciary effluents	100% positive samples for HAdV in all steps of the treatment. Removal of HAdV within primary and secondary treatments 1.03 log 10 (89%) and UV disinfection process 0.13 log 10 (11%)
Ye et al., 2012 [61]	Heim et al., 2003 [35]	River and drinking water	100% positive samples (24/24). Mean values in river 2.28E + 04 GC/L