Table 6.

Effect of C. latifolia extracts on ALT, GGT, urea, and creatinine levels in HFD and low dose STZ induced diabetic rats.

Group	ALT (U/L)		GGT (U/L)		Urea (mmol/L)		Creatinine (mmol/L)
	Before	After	Before	After	Before	After	Before	After
1	75.12 ± 2.34	109.24 ± 3.42	6.73 ± 1.19	5.04 ± 0.69	5.51 ± 0.33	5.89 ± 0.51	31.30 ± 1.11	30.97 ± 2.52
2	88.24 ± 1.55	114.81 ± 5.10	8.65 ± 2.12	10.32 ± 0.52*	5.07 ± 0.14	5.82 ± 0.37	49.40 ± 2.54	62.90 ± 3.46*
3	89.12 ± 3.42	149.65 ± 4.26*	13.11 ± 1.31*	27.88 ± 2.37*	4.53 ± 0.35	6.83 ± 0.40	52.85 ± 2.68	72.10 ± 2.58*
4	77.50 ± 2.27	76.49 ± 1.33*	9.53 ± 1.34	5.39 ± 0.89*	9.61 ± 0.16*	6.66 ± 0.25	58.80 ± 2.34	47.80 ± 1.19
5	76.21 ± 3.17	84.77 ± 2.50*	9.07 ± 1.28	3.18 ± 1.41	12.55 ± 0.42	5.66 ± 0.26*	59.13 ± 1.19	51.40 ± 0.77
6	80.50 ± 1.24	78.10 ± 2.46*	9.25 ± 1.31	5.10 ± 0.17*	9.15 ± 0.36	6.65 ± 0.41	51.93 ± 0.76	42.60 ± 0.15
7	85.74 ± 5.31	83.10 ± 3.26*	8.90 ± 1.19	5.84 ± 0.21*	14.62 ± 0.54*	4.98 ± 0.33	57.63 ± 0.50	56.21 ± 0.32

Data are means ± SD for ALT, GGT, urea and creatinine levels of normal rats (Group 1), obese rats (Group 2), diabetic control rats (Group 3), diabetic rats treated with 50 mg/kg bw of C. latifolia fruit:root extracts (Group 4), diabetic rats treated with 100 mg/kg bw of C. latifolia fruit:root extracts (Group 5), diabetic rats treated with 200 mg/kg bw of C. latifolia fruit:root extracts (Group 6), and diabetic rats treated with 10 mg/kg bw of glibenclamide (Group 7).

Significant difference is at *P < 0.05 when compared with diabetic control rats (Group 3).