Table 2.
Screening anti-inflammation targets over molecule docking of compounds 1–5.
| Compound number | Molecules docking results | ||
|---|---|---|---|
| Target name | Fit score | Norm fit score | |
| Dual specificity mitogen-activated protein kinase kinase 1 (MPKK1) | 4.111 | 0.4567 | |
| Glucocorticoid receptor (GR) | 4.010 | 0.5012 | |
| Prothrombin | 3.843 | 0.4271 | |
| 1/2 | Alpha-1-antitrypsin | 3.834 | 0.6390 |
| Glycogen synthase kinase-3 beta | 3.786 | 0.5409 | |
| ADAM 17 | 3.726 | 0.9315 | |
| Tyrosine-protein kinase SYK | 3.712 | 0.6187 | |
| Protein kinase C theta type | 3.701 | 0.5287 | |
|
| |||
| Dual specificity mitogen-activated protein kinase kinase 1 (MPKK1) | 5.171 | 0.5745 | |
| Proto-oncogene tyrosine-protein kinase LCK | 4.370 | 0.4370 | |
| 3 | Glucocorticoid receptor | 4.332 | 0.5415 |
| Glycogen synthase kinase-3 beta | 4.298 | 0.6140 | |
| Cathepsin B | 4.110 | 0.4566 | |
| Peroxisome proliferator-activated receptor alpha | 4.042 | 0.5053 | |
| Prothrombin | 3.988 | 0.6646 | |
|
| |||
| Dual specificity mitogen-activated protein kinase kinase 1 (MPKK1) | 3.660 | 0.4067 | |
| 4 | Proto-oncogene tyrosine-protein kinase LCK | 3.596 | 0.5137 |
| Prothrombin | 3.496 | 0.3885 | |
| Leukotriene A-4 hydrolase | 3.354 | 0.3727 | |
|
| |||
| Dual specificity mitogen-activated protein kinase kinase 1 (MPKK1) | 4.246 | 0.4718 | |
| Glucocorticoid receptor | 3.931 | 0.4913 | |
| Estrogen receptor | 3.728 | 0.5325 | |
| Leukocyte elastase | 3.709 | 0.4121 | |
| 5 | Protein kinase C theta type | 3.689 | 0.5270 |
| Glycogen synthase kinase-3 beta | 3.642 | 0.5203 | |
| Proto-oncogene tyrosine-protein kinase LCK | 3.626 | 0.6044 | |
| Mitogen-activated protein kinase 10 | 3.596 | 0.5137 | |
| Peroxisome proliferator-activated receptor alpha | 3.576 | 0.4470 | |