Table 3.

Change from baseline in hsCRP and body weight at 6 and 24 months by subgroup among participants (n=710)

Characteristic	Baseline CRP median (IQR)	P value between groups at baseline	6m median hsCRP change from baseline in mg/L (median % change)	P value between groups for % hsCRP change	6m median change from baseline in wt in kg (median % change)	P value between groups for % wt change	24 median hsCRP change from baseline in mg/L (median % change)	P value between groups for % hsCRP change	24m median change from baseline in wt in kg (median % change)	P value between groups for % wt change
Gender:
Female (n=435)	2.2 (1.1,4.3)		−0.4 (−24%)		−5.8 (−6.5%)		−0.3 (−20%)		−2.8 (−3.2%)
Male (n=275)	1.6 (0.8,2.7)	<.0001	−0.4 (−27%)	0.31	−6.8 (−6.8%)	0.81	−0.3 (−28%)	0.08	−3.9 (−3.7%)	0.28
Race:
Caucasian (n=579)	1.8 (0.9,3.4)		−0.4 (−25%)		−6.6 (−7.2%)		−0.3 (−24%)		−3.7 (−4.1%)
Black (n=100)	2.4 (1.2,4.8)	0.0032	−0.5 (−24%)	0.65	−3.9 (−4.2%)	<.0001	−0.4 (−21%)	0.70	−1.0 (−1.1%)	.0011
Age:
≤50 years old (n=295)	1.8 (0.8,3.6)		−0.4 (−23%)		−5.6 (−6.0%)		−0.2 (−23%)		−2.8 (−3.0%)
>50 years old (n=415)	1.9 (0.9,3.5)	0.64	−0.4 (−28%)	0.34	−6.5 (−7.2%)	0.0149	−0.4 (−23%)	0.32	−3.5 (−4.0%)	.0362
BMI:
<30 (n=180)	1.2 (0.6,2.4)		−0.2 (−24%)		−6.0 (−7.3%)		−0.2 (−21%)		−2.8 (−3.6%)
≥30 (n=493)	2.2 (1.1,4.1)	<.0001	−0.5 (−25%)	0.34	−6.4 (−6.5%)	0.72	−0.4 (−23%)	0.21	−3.5 (−3.5%)	0.67
Lipid lowering medicine:
Yes (n=135)	1.4 (0.7,2.6)		−0.3 (−32%)		−6.6 (−6.8%)		−0.2 (−22%)		−4.0 (−4.3%)
No (n=575)	2.0 (0.9,3.8)	0.0019	−0.4 (−24%)	0.38	−6.1 (−6.7%)	0.48	−0.4 (−22%)	0.87	−2.9 (−3.3%)	0.26
Use of hormones among post-menopausal women:
Yes (n=80)	2.9 (1.5,4.7)		−0.8 (−26%)		−7.0 (−8.6%)		−0.6 (−37%)		−2.1 (−2.2%)
No (n=161)	1.8 (1.0,3.4)	0.0029	−0.4 (−24%)	0.64	−5.7 (−6.4%)	0.17	−0.3 (−19%)	0.0139	−3.7 (−4.7%)	0.55