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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Kidney Int. 2013 Jun;83(6):991–993. doi: 10.1038/ki.2013.94

Figure 1. Diagram illustrating roles of urea channels in the process responsible for accumulation of urea in renal inner medulla.

Figure 1

See text for explanation. DVR, descending vasa recta; AVR, ascending vasa recta; OS-OM, outer stripe of outer medulla; IS-OM, inner stripe of outer medulla; IM, inner medulla; IMCD, inner medullary collecting duct. UT-B, UT-A1, UT-A2, and UT-A3 are urea channel isoforms described in the text.