Table 3.
Changes in sexual risk behaviors and male partner risk behaviors from baseline to 18 months, HVTN 906
| Baseline (n=799) |
6-mos (n=686) |
12-mos (n=661) |
18-mos (n=632) |
p-valuea baseline to 18 mos |
p-valuea 6 to 18 mos |
|
|---|---|---|---|---|---|---|
|
| ||||||
| In past 6 months: | % | % | % | % | ||
| Median no. of male partners (25th, 75th %tile) | 3 (2,7) | 2 (1,3) | 1(1,3) | 1(1,3) | <0.0001 | 0.001 |
| Had a new partner | 54.7 | 38.9 | 33.1 | 31.2 | <0.0001 | 0.002 |
| Had unprotected vaginal sex | 99.6 | 81.8 | 79.0 | 76.1 | <0.0001 | 0.006 |
| Had unprotected anal sex | 24.0 | 11.5 | 10.7 | 8.3 | <0.0001 | 0.06 |
| Had unprotected sex while drunk or high | 73.4 | 59.5 | 56.4 | 53.3 | <0.0001 | 0.009 |
| Had unprotected sex while partner was drunk or high | 72.2 | 53.7 | 53.4 | 50.4 | <0.0001 | Ns |
| Exchanged sex | 52.3 | 37.0 | 35.6 | 33.1 | <0.0001 | 0.02 |
| Crack cocaine use | 49.4 | 37.8 | 33.7 | 35.2 | <0.0001 | ns |
| Marijuana use | 47.4 | 35.1 | 35.6 | 31.3 | <0.0001 | 0.06 |
| Heavy alcohol useb | 31.0 | 20.7 | 20.6 | 19.5 | <0.0001 | ns |
| Heroin use | 26.7 | 22.0 | 20.0 | 19.7 | <0.0001 | 0.02 |
| Cocaine use | 11.6 | 6.0 | 3.3 | 3.8 | <0.0001 | 0.04 |
| Had a male partner who had concurrent female partners | ||||||
| Yes | 57.3 | 32.0 | 28.8 | 23.3 | <0.0001 | <0.0001 |
| Don’t Know | 31.8 | 38.5 | 40.5 | 41.3 | ||
| Had a male partner who was incarcerated | ||||||
| Yes | 37.0 | 17.6 | 15.1 | 13.0 | <0.0001 | 0.03 |
| Don’t Know | 21.9 | 15.5 | 14.7 | 12.1 | ||
| Had a male partner who injected drugs | ||||||
| Yes | 11.1 | 3.6 | 3.5 | 3.5 | <0.0001 | ns |
| Don’t Know | 27.0 | 13.3 | 12.7 | 12.1 | ||
| Had a male partner who had sex with men | ||||||
| Yes | 4.0 | 1.5 | 1.4 | 1.4 | ns | ns |
| Don’t Know | ||||||
| Diagnosed/treated for STI or symptoms | 26.7 | 16.0 | 14.3 | 16.2 | <0.0001 | ns |
p-values were from score test statistics testing the null hypothesis that the behavior is the same at the two time points in the context of a GEE model using an exchangeable correlation structure and adjusted for predictors of drop-out (age, ethnicity/race, moved in the year prior to the screening visit, and at baseline reported a male partner who had been incarcerated). Male partner risk behaviors were categorized as yes vs no/don’t know for statistical testing.
Heavy alcohol use was defined as drinking 4 or more drinks every day or drinking 6 or more drinks on a typical day that the woman consumed alcohol.
ns= statistically non-significant (p-value > 0.05)