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. 2013 Mar 6;33(10):4540–4549. doi: 10.1523/JNEUROSCI.5024-12.2013

Figure 4.

Figure 4.

NMRP expression PD: absence of tremor effect. NMRP expression values computed in atremulous (Tremor(−)) PD patients were compared with corresponding values from their age- and severity-matched counterparts with observable tremor (Tremor(+)) as well as measurements in normal (NL) control subjects. A, Pattern expression in the nonmovement condition (NMRP [NO MOVE]) was increased to similar levels in tremulous and atremulous patients, with significant elevations in both PD subgroups relative to healthy control values (p < 0.04). B, Group differences in NMRP expression measured during motor execution (MOVE) were not significant (F(2,25) = 1.421, p = 0.260). C, A significant difference across groups was noted for ΔNMRP [MOVE − NO MOVE], the network-level motor activation response (F(2,25) = 7.533, p = 0.003). ΔNMRP was abnormally reduced in the tremulous PD subgroup (p = 0.002; post hoc Bonferroni test). A trend-level reduction (p = 0.1) in ΔNMRP was evident in the atremulous PD subgroup relative to healthy control subjects. The two PD subgroups, however, did not differ with respect to this measure (p = 0.293). *p < 0.05 (post hoc Bonferroni test). **p < 0.01 (post hoc Bonferroni test).