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. Author manuscript; available in PMC: 2013 Jun 4.
Published in final edited form as: Ann Neurol. 2011 Oct;70(4):646–656. doi: 10.1002/ana.22528

Figure 2. Flow cytometric analysis of inflammatory infiltrate following ICH.

Figure 2

Brain flow cytometry results after ICH surgery. (A) Gating strategy of live cells to identify all blood-derived leukocytes (CD45hi), neutrophils (CD45hiCD3−CD19−NK1.1−CD11b+Ly6G+), monocytes (CD45hiCD3−CD19−NK1.1−CD11b+Ly6G−CD11c−GR1−), inflammatory monocytes (CD45hiCD3−CD19−NK1.1−CD11b+Ly6G−CD11c−GR1+) and dendritic cells (CD45hiCD3−CD19−NK1.1−CD11b+Ly6G−CD11c+). (B–F) Differences in each cell population between days 1 and 3 post-ICH in WT and TLR4-deficient mice. Data expressed as mean ± SEM excess ipsilateral cells, *= p<0.05 with correction for multiple comparisons, n=4 / genotype on day 1 post-ICH and n=6 /genotype on day 3 post-ICH.