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. Author manuscript; available in PMC: 2013 Jun 4.
Published in final edited form as: Ann Neurol. 2011 Oct;70(4):646–656. doi: 10.1002/ana.22528

Figure 6. Quantification of brain leukocyte populations after blood transfer experiments.

Figure 6

Creating ICH with blood from a donor mouse of the opposite genotype altered the composition of the inflammatory cells in the ipsilateral hemisphere. (A) Total blood-derived leukocytes were reduced in the WT mice with a TLR4-deficient ICH and increased in the TLR4-deficient mice given a WT ICH. (B) Neutrophil counts were not altered by the blood transfer. (C) Inflammatory monocytes were reduced in the WT mice with TLR4-deficient ICH. (D) Similar to total leukocytes, monocytes were reduced in the WT mice with a TLR4-deficient ICH and increased in the TLR4-deficient mice given a WT ICH. (E) Dendritic cell counts were not affected by the blood transfer. (F) Microglia counts were reduced in both the WT mice given a TLR4-deficient ICH and the TLR4-deficient mice given a WT ICH. n=6–7/group, * p<0.05.