Table 4.
Characteristics of Study Participants and Levels of 8-oxodG, Determined by UHPLC-MS/MS (Performed by Laboratory 9)
| Mean | Range | Men | Women | |
|---|---|---|---|---|
| Age (years) | 38 | 23–59 | 39 | 38 |
| Weight (kg) | 74 | 53–97 | 82 | 63** |
| BMI | 24 | 19–29 | 25 | 23** |
| Creatinine mmol/24 h | 15.5 | 8.5–25.3 | 17.9 | 12.3** |
| Urinary volume (L/24 h) | 1.97 | 0.85–4.57 | 1.82 | 2.18 |
| UHPLC-MS/MS | ||||
| 8-oxodG (nM) | 16.7 | 5.8–33.4 | 19.2 | 13.2* |
| 8-oxodG/SG 1.018 (nM) | 19.1 | 11.0–34.6 | 19.4 | 18.6 |
| 8-oxodG (nmol/24 h) | 28.5 | 12.7–49.7 | 31.2 | 24.7a |
| 8-oxodG (nmol/mmol creatinine) | 1.88 | 0.95–3.10 | 1.79 | 2.00 |
Study participants were 26 healthy nonsmoking Swedish subjects (11 women and 15 men). The means of two separate 24 h urine samples (from n=26 individuals) are given. Men vs. women: *p<0.05; **p<0.01; ap=0.06.