Table 4.
Relationship between the serum levels of the studied factors and presence or absence of hypertension in patients with proliferative diabetic retinopathy.
| Presence of hypertension | P value | ||
|---|---|---|---|
| Yes (mean ± s.d) |
No (mean ± s.d) |
||
| BDNF (ng/mL) | 10.1 ± 7.7 | 10.3 ± 8.0 | 0.907 |
| HMGB1 (ng/mL) | 4.4 ± 2.3 | 4.5 ± 1.8 | 0.565 |
| MCP-1 (pg/mL) | 244.9 ± 156.0 | 300.2 ± 199.4 | 0.489 |
| TBARS (μM) | 24.2 ± 11.2 | 35.7 ± 28.5 | 0.356 |
| sICAM-1 (ng/mL) | 213.0 ± 118.9 | 194.1 ± 61.8 | 0.756 |
| sRAGE (pg/mL) | 1050.5 ± 536.2 | 686.5 ± 474.2 | 0.017* |
*Statistically significant at 5% level of significance.
BDNF: brain-derived neurotrophic factor; HMGB1: high-mobility group box-1; MCP-1: monocyte chemoattractant protein-1; TBARS: thiobarbituric acid reactive substance; sICAM-1: soluble intercellular adhesion molecule-1; sRAGE: soluble receptor for advanced glycation end products.