Table 1.
Summary of null mutants in AcMNPV generated in BACmid DNA by ET recombination.
| Virus function | Gene deleted | References |
|---|---|---|
| DNA replication | helicase (p143), lef3, lef5, lef6, lef11, alk-exo, dna-pol | [70, 71, 94–100] |
| Transcription | ie-0 and ie-1 | [101] |
| Cell entry | ac23, gp64 | [47, 102, 103] |
| Infectivity in insects | ac96, p74 | [104, 105] |
| Nucleocapsid assembly | p6.9, ac53, vlf-1, 38K, ac101, ac142, ac144, ac109 | [106–112] |
| Nucleocapsid release from the nucleus | exon0, ac66, vp80 | [22, 85, 113–115] |
| Formation of enveloped virus | ac142, p48, ac76, odv-e18, odv-e56 | [47, 116–118] |
| Interaction with host | egt, chiA, v-cath, IAP2 | [47] |
| Unknown, essential genes | ac92, ac-fgf, ac11, ac-pe | [47, 119] |
| Unknown, non-essential genes | me53, ac18, ac-ctx | [47, 120, 121] |