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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Am J Transplant. 2013 Mar 6;13(5):1193–1202. doi: 10.1111/ajt.12194

Figure 1.

Figure 1

CML and co-culture CMLs demonstrated that DST in LTT animals increased suppression of the anti-donor response in vitro. CTL and co-culture CTL assays were set up one week before and one week after the DST. Recipient responses to donor stimulation are shown with solid lines and boxes; third party stimulation are shown with dotted lines and striped boxes. (a) While the anti-donor CTLs were 16% and 20% respectively before the DST, there were no anti-donor CTL responses 1 week after the DST. (b) Cells from the LTT animal primed by donor antigens specifically suppressed the naïve CTL responses against donor-type cells 70% and 80% respectively before the DST, and completely (red line with an arrow) after the DST.