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. Author manuscript; available in PMC: 2013 Jun 4.
Published in final edited form as: Mol Cell Biochem. 2009 Jul 8;333(0):9–26. doi: 10.1007/s11010-009-0199-x

Scheme 1.

Scheme 1

Proposed mechanism of glyoxal-induced cytotoxicity, cytoskeletal reorganization, barrier dysfunction, and inhibition of angiogenesis in endothelial cells and aminoguanidine protection