TABLE 1.
Annotated gene coding for glycoside hydrolases putatively involved in HMO degradation as described at the CAZy database (http://www.cazy.org)
GH2 | GH16 | GH18 | GH20 | GH29 | GH33 | GH95 | |
---|---|---|---|---|---|---|---|
Bacteroides fragilis ATCC25285 | 15 | 6 | 2 | 12 | 9 | 3 | 4 |
Bacteroides vulgatus ATCC8483 | 25 | 1 | 2 | 8 | 8 | 2 | 4 |
Bifidobacterium infantis ATCC15697 | 2 | – | 1 | 3 | 3 | 2 | 1 |
Bifidobacterium bifidum NCIMB 4117 | 3 | – | – | 4 | 1 | 1 | 1 |
The selected glycoside hydrolase families include the following activities: GH2, α-galactosidase; GH16, endo-β-1,4-galactosidase; GH18, endo-β-N-acetylglycosaminidase; GH20, β-hexosaminidase; GH29, α-1,3/4-fucosidase; GH33, sialidase; GH95, α-1,2-fucosidase.