. Author manuscript; available in PMC: 2013 Jun 4.

Published in final edited form as: Mol Genet Metab. 2010 Jan 12;99(4):333–345. doi: 10.1016/j.ymgme.2009.12.007

Table 7.

Red blood cell membrane fatty acids (mg%) as mean (SD) values.

Fatty acid species	Control children, N = 54	MSUD pre-trial formula, N = 78	MSUD study formula, N = 15	ANOVA p value
18:2n – 6, linoleic	9.72 (1.08)	12.20 (1.69)^a	11.47 (0.80)^a	<0.0001
20:4n – 6, arachadonic (AA)	15.63 (1.31)	13.73 (1.29)^a	12.26 (0.96)^a,^d	<0.0001
22:4n – 6, adrenic	3.84 (0.62)	4.38 (0.71)^a	2.50 (0.34)^a,^d	<0.0001
22:5n – 6, docosapentaenoic	0.90 (0.24)	0.79 (0.24)^c	0.38 (0.07)^a,^d	<0.0001
18:3n – 3, alpha-linolenic	0.27 (0.19)	0.20 (0.17)	0.54 (0.06)^a,^d	<0.0001
20:5n – 3, eicosapentaenoic (EPA)	0.34 (0.09)	0.18 (0.14)^a	0.75 (0.12)^a,^d	<0.0001
22:5n – 3, docosapentaenoic	1.92 (0.29)	1.60 (0.62)^b	3.36 (0.27)^a,^d	<0.0001
22:6n – 3, docosahexaenoic (DHA)	3.73 (1.14)	1.78 (0.74)^a	2.38 (0.46)^a,^e	<0.0001
Mean DHA/alpha-linolenic ratio	14.0	8.9	4.4	–
Mean DHA/EPA ratio	11.0	9.9	3.2	–
Total saturates	38.47 (1.27)	38.82 (1.64)	39.10 (0.53)	NS
Total n – 6 fatty acids	32.96 (1.68)	35.00 (2.07)^a	29.33 (0.84)^a,^d	<0.0001
Total n – 3 fatty acids	6.31 (1.26)	3.82 (1.37)^a	7.06 (0.51)^d	<0.0001

Different than control children, Tukey p value <0.001.

Tukey p value <0.0.

Tukey p value <0.05.

Different than MSUD pre-trial, Tukey p value <0.001.

Tukey p value <0.05; NS, not significant (ANOVA p > 0.05).