Figure 7.
The cortico-striatal circuitry, neurotransmitters, and their receptors involved in the 5-CSRT task. (a) The behavioral outcome and changes in GLU, DA, and GABA levels in the mPFC and dm-STR caused by CPP injected into the mPFC. (b, c) Schematic representations of the proposed sites of action and the behavioral outcomes resulting from blockade of D1-like or D2-like receptors by antagonists SCH23390 (b) and haloperidol (c) in the dm-STR of rats injected in the mPFC with CPP. The symbols represent: (↑) increase; (↓) decrease; (=) no effect; or (+) reversal of the CPP-induced effects.