Table 2. Total Cellular Protein Levels of NR2B and GluR1 Were Differentially Expressed in MPFC and Hippocampus, 24 h Following Treatment with Either GLYX-13 (3 mg/kg, IV) or Ketamine (10 mg/kg, IV), as Measured by Western Blot. Data are Expressed as Mean±SEM % of Control Levels.
NR2B | GluR1 | |
---|---|---|
MPFC 24 h | ||
Vehicle | 100±26 | 100±10 |
GLYX-13 | 242±38* | 104±17 |
Ketamine | 196±28* | 95±15 |
Hippocampus 24 h | ||
Vehicle | 100±21 | 100±7 |
GLYX-13 | 129±19 | 116±8 |
Ketamine | 89±13 | 116±2 |
n=4–11 per group.
*P<0.05, Fisher's PLSD post hoc test vs vehicle.