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. 2013 Jan 16;38(5):817–825. doi: 10.1038/npp.2012.247

Figure 3.

Figure 3

(a) Oxidative stress index and (b) SOD activity in Aβ25–35-injected PLTP-KO mice. WT and PLTP-KO mice, supplemented in vitamin E (KOE) or not (KO), received an i.c.v. injection of sterile water (V) or Aβ25–35, 3 nmol (Aβ3). They were killed after 7 days. Oxidative stress was measured in cortex homogenates using a fluorescent probe. SOD activity was measured using a spectrophotometric assay kit. One-way ANOVA: F(4,102)=5.17, P<0.001, n=17–24 in (a); F(4,27)=4.90, P<0.01, n=3–7 in (b). *P<0.05, **P<0.01 vsV-treated WT group; #P<0.05 vs Aβ3-treated WT group; §P<0.05 vs Aβ3-treated PLTP-KO group; Bonferroni's test.